Français Anglais
Accueil Annuaire Plan du site
Accueil > Evenements > Séminaires
Séminaire d'équipe(s) BioInfo
Sequence-based identification of RNA 3D structural modules
José Cruz Almeida

10 May 2012, 14h30 - 10 May 2012, 15h30
Salle/Bat : 465/PCRI-N
Contact : aze@lri.fr

Activités de recherche :

Résumé :
Structural RNA modules consist of sets of ordered non-Watson-Crick base pairs embedded between Watson-Crick pairs recurrently observed in RNA families throughout the phylogeny. They play central roles as architectural organizers and sites of ligand binding in RNA molecules. Here we describe a computational tool for the detection of structural modules in single and multiple RNA sequences Structural RNA modules consist of sets of ordered non-Watson-Crick base pairs embedded between Watson-Crick pairs recurrently observed in RNA families throughout the phylogeny. They play central roles as architectural organizers and sites of ligand binding in RNA molecules. Here we describe a computational tool for the detection of structural modules in single and multiple RNA sequences
in the absence of any other information. We systematically search four of the most common RNA modules (G-bulges, Kink-turns, C-loops and tandem-GAs), in the 1,444 publicly available RNA alignments of RFam where we've found 21 yet unreported modules. Finally we'll discuss the strengths and limitations of the approach and some open problems in the domain of structural module discovery.

Pour en savoir plus :
Séminaires
Refining Transitive and Pseudo-Transitive Relation
Gestion de données du Web
Monday 24 January 2022 - 13h00
Salle : 455 - PCRI-N
Shuai Wang .............................................

Discovering Causal Rules in Knowledge Graphs using
Intégration de données et de connaissances
Monday 10 January 2022 - 15h00
Salle : 455 - PCRI-N
Lucas Simonne .............................................

Meta-Learning for Few-Shot Link Prediction in Know
Intégration de données et de connaissances
Monday 13 December 2021 - 13h00
Salle : 455 - PCRI-N
Taha Halal .............................................

Knowledge Graph Refinement based on Triplet BERT-N
Gestion de données du Web
Monday 29 November 2021 - 13h00
Salle : 455 - PCRI-N
Armita Khajeh Nassiri .............................................

A Hyper-graph Approach for Computing EL+-Ontology
Raisonnement automatique
Monday 15 November 2021 - 13h00
Salle : 445 - PCRI-N
Hui Yang .............................................